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首頁 /藥靶模型 /GPCR靶點(diǎn)細(xì)胞 /Class A(Rhodopsin) /GPR120/CHO

GPR120/CHO

CBP71105

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I. Background
GPR120 is a GPCR that responds to long-chain FAs. This receptor was recently shown to be expressed in macrophages, where it is coupled to the β-arrestin pathway.
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: N/A
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for GPR120 receptor

Transducer: Gq/G11 family
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1.Dose Response of TUG-891 in GPR120 CHO Cells (C1).


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