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首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細(xì)胞 /Class A(Rhodopsin) /AGTR1/CHO

AGTR1/CHO

CBP71314

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I. Background

AGTR1 (Angiotensin II Receptor Type 1) is a Protein Coding gene. Diseases associated with AGTR1 include Renal Tubular Dysgenesis and Hypertension, Essential. Among its related pathways are Signaling by GPCR and ADP signalling through P2Y purinoceptor 1. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and angiotensin type II receptor activity.

 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assays for AGTR1 receptor

Transducer: Gq/G11
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1. HTRF IP One Assay with AGTR1(AT1) CHO Cells(C18).


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