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TP53 p.E180fs Reference Standard

CBP10435

產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction 
Gene TP53
Description TP53, cellular tumor antigen p53, is a tumor suppressor (PMID: 30562755) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types cancers (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457).
   
Technical Data 
DNA Change c.539delA
AA Change p.E180fs
Mutation type Frame_Shift_Del
Zygosity Homozygous
Allelic Frequency 100.00%
Transcript ENST00000269305.4
Cosmic ID N/A
Chr position(GRCh37) chr17:7578391
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

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